Hypertrophic subaortic stenosis with myocardial fibre degeneration.
نویسنده
چکیده
During the past decade it has become evident that obstruction to left ventricular outflow may result from causes other than aortic valve disease and congenital subaortic stenosis associated with a demonstrable ridge or diaphragm below the aortic valve. Various types of obstruction have been demonstrated, sometimes associated with marked local hypertrophy of the myocardium, especially the interventricular septum, and sometimes with generalized hypertrophy of the left ventricle. This obstructive syndrome has been described under a variety of names, functional obstruction of the left ventricle (Brock, 1957, 1959), pseudo aortic stenosis (Bercu et al., 1958), asymmetrical hypertrophy of the heart (Teare, 1958), obstructive cardiomyopathy (Goodwin et al., 1960), and hypertrophic subaortic stenosis (Brockenbrough, Braunwald, and Morrow, 1961), Under the title "Familial muscular subaortic stenosis" Brent et al. (1960) described a group of cases in which several members of two families were involved. Necropsy studies have sometimes shown pronounced localized hypertrophy of the interventricular septum or generalized hypertrophy of the left ventricle. Histologically the only changes found have been hypertrophy of the muscle fibres, occasionally fine fibrosis and slight endocardial fibrosis over the area of obstruction. The following is a report of a case which, in addition to hypertrophy, showed extensive myocardial fibre degeneration.
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عنوان ژورنال:
- British heart journal
دوره 27 5 شماره
صفحات -
تاریخ انتشار 1965